Search on: ANTI-ARRHYTHMIA AGENTS 
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Descriptor English:   Anti-Arrhythmia Agents 
Descriptor Spanish:   Antiarrítmicos 
Descriptor Portuguese:   Antiarrítmicos 
Synonyms English:   Antifibrillatory Agents
Cardiac Depressants
Myocardial Depressants  
Tree Number:   D27.505.954.411.097
Definition English:   Agents used for the treatment or prevention of cardiac arrhythmias. They may affect the polarization-repolarization phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibers. Anti-arrhythmia agents are often classed into four main groups according to their mechanism of action: sodium channel blockade, beta-adrenergic blockade, repolarization prolongation, or calcium channel blockade. 
Indexing Annotation English:   consider also ARRHYTHMIAS, CARDIAC /drug ther
See Related English:   Adrenergic beta-Antagonists
Calcium Channel Blockers
 
History Note English:   76; was NON MESH before 1976; MYOCARDIAL DEPRESSANTS was heading 1963-75 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DU diagnostic use
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   902 
Unique Identifier:   D000889 

Occurrence in VHL:
 

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